Maternal education modifies the age-related increase in the birth prevalence of Down syndrome

Maternal education modifies the age-related increase in the birth prevalence of Down syndrome

Objective To test the hypothesis that the age‐related increase in the birth prevalence of Down syndrome is less for women with higher levels of education due to their more frequent use of prenatal diagnosis. Methods We compared the effects of maternal age on the odds of Down syndrome at birth, and o...

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Veröffentlicht in:Prenatal diagnosis 2004-02, Vol.24 (2), p.79-82
Hauptverfasser: Khoshnood, Babak, Wall, Stephen, Pryde, Peter, Lee, Kwang-sun
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biological and medical sciences
Chromosome aberrations
Cohort Studies
Down syndrome
Down Syndrome - epidemiology
Educational Status
Ethnic Groups
ethnicity
Female
Gynecology. Andrology. Obstetrics
Humans
Logistic Models
Management. Prenatal diagnosis
Maternal Age
maternal education
Medical genetics
Medical sciences
Odds Ratio
Pregnancy. Fetus. Placenta
prenatal diagnosis
Prenatal Diagnosis - statistics & numerical data
Prevalence
United States - epidemiology
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Zusammenfassung:Objective To test the hypothesis that the age‐related increase in the birth prevalence of Down syndrome is less for women with higher levels of education due to their more frequent use of prenatal diagnosis. Methods We compared the effects of maternal age on the odds of Down syndrome at birth, and on amniocentesis use, in women with
ISSN:0197-3851
1097-0223
DOI:10.1002/pd.749