First three examples of taxane-derived di-propellanes in Taxus canadensis needles

The first three examples of taxane-derived [3.3.3][3.4.5] di-propellanes isolated from the needles of a yew tree are reported. They differ in their acetylation pattern and their biogenesis from a putative taxane precursor is proposed.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2004-03 (5), p.544-545
Hauptverfasser: Shi, Qing Wen, Sauriol, Françoise, Lesimple, Alain, Zamir, Lolita O
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Sprache:eng
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Zusammenfassung:The first three examples of taxane-derived [3.3.3][3.4.5] di-propellanes isolated from the needles of a yew tree are reported. They differ in their acetylation pattern and their biogenesis from a putative taxane precursor is proposed.
ISSN:1359-7345
DOI:10.1039/b316051c