Frequency of nonresponse antiplatelet activity of clopidogrel during pretreatment for cardiac catheterization

Frequency of nonresponse antiplatelet activity of clopidogrel during pretreatment for cardiac catheterization

Platelet function was evaluated before and after clopidogrel therapy in 50 cardiology candidates scheduled for intervention; results were averaged from optical platelet aggregation with 2 significantly correlated point-of-care instruments, Thrombelastograph and Ichor PlateletWorks. Although this was...

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Veröffentlicht in:The American journal of cardiology 2004-02, Vol.93 (4), p.456-458
Hauptverfasser: Mobley, Joseph E., Bresee, Stuart J., Wortham, Dale C., Craft, Robert M., Snider, Carolyn C., Carroll, Roger C.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Aged, 80 and over
Analysis
Biological and medical sciences
Blood
Cardiac Catheterization
Cardiology. Vascular system
Cardiovascular disease
Catheters
Drug therapy
Female
Heart
Humans
Male
Medical sciences
Medical treatment
Middle Aged
Platelet Aggregation Inhibitors - pharmacology
Platelet Function Tests
Point-of-Care Systems
Ticlopidine - analogs & derivatives
Ticlopidine - pharmacology
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Zusammenfassung:Platelet function was evaluated before and after clopidogrel therapy in 50 cardiology candidates scheduled for intervention; results were averaged from optical platelet aggregation with 2 significantly correlated point-of-care instruments, Thrombelastograph and Ichor PlateletWorks. Although this was a limited study with few complications, the failure of clopidogrel therapy (30% nonresponders with
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2003.10.042