Pefloxacin in the treatment of septicaemia: three years' experience

Sixty cases of septicaemia treated with pefloxacin, alone (30) or in combination with other antibiotics (30) were analysed retrospectively. A satisfactory outcome was achieved in 33 (87%) of 38 evaluable Gram-negative septicaemias (including success in 25 of 29 treated with pefloxacin alone) and in...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1990, Vol.26 (suppl-B), p.97-101
Hauptverfasser:	Bernard, E., Durant, J., Elbaze, Ph, Dellamonica, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Anti-Bacterial Agents Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Drug Therapy, Combination - administration & dosage Drug Therapy, Combination - therapeutic use Escherichia coli Infections - drug therapy Female Humans Klebsiella Infections - drug therapy Male Medical sciences Middle Aged Pefloxacin - administration & dosage Pefloxacin - therapeutic use Pharmacology. Drug treatments Proteus Infections - drug therapy Retrospective Studies Sepsis - drug therapy Time Factors
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Beschreibung
Zusammenfassung:	Sixty cases of septicaemia treated with pefloxacin, alone (30) or in combination with other antibiotics (30) were analysed retrospectively. A satisfactory outcome was achieved in 33 (87%) of 38 evaluable Gram-negative septicaemias (including success in 25 of 29 treated with pefloxacin alone) and in 15 of 21 staphylococcal septicaemias, mainly treated with combinations of antibiotics. Failures and relapses were associated with a variety of local or systemic underlying conditions.
ISSN:	0305-7453 1460-2091
DOI:	10.1093/jac/26.suppl_B.97