Mechanisms maintaining antibody-induced enhancement of allografts. III, Examination of graft-versus-host reactivity of T cell subsets from rats with long-surviving grafts

In this study, we examined whether there was an associated change in the capacity of T cell subsets from enhanced animals with long-surviving allografts to proliferate in a PLN GVH assay. We also examined the capacity of unfractionated cells from these animals to mediate lethal GVHD, as this assay b...

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Veröffentlicht in:Transplantation 1990-12, Vol.50 (6), p.1078-1081
Hauptverfasser: PEARCE, N. W, DORSCH, S. E, HALL, B. M
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creator PEARCE, N. W
DORSCH, S. E
HALL, B. M
description In this study, we examined whether there was an associated change in the capacity of T cell subsets from enhanced animals with long-surviving allografts to proliferate in a PLN GVH assay. We also examined the capacity of unfractionated cells from these animals to mediate lethal GVHD, as this assay better reflects the effector phase of graft rejection (DBO).
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subjects Animals
Biological and medical sciences
CD4 Antigens - analysis
Experimental and animal immunopathology. Animal models
Graft Survival
Graft vs Host Disease - immunology
Graft vs Host Reaction
Immunopathology
Lymph Nodes - pathology
Medical sciences
Rats
T-Lymphocyte Subsets - immunology
Transplantation, Homologous
title Mechanisms maintaining antibody-induced enhancement of allografts. III, Examination of graft-versus-host reactivity of T cell subsets from rats with long-surviving grafts
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