Mechanisms maintaining antibody-induced enhancement of allografts. III, Examination of graft-versus-host reactivity of T cell subsets from rats with long-surviving grafts

In this study, we examined whether there was an associated change in the capacity of T cell subsets from enhanced animals with long-surviving allografts to proliferate in a PLN GVH assay. We also examined the capacity of unfractionated cells from these animals to mediate lethal GVHD, as this assay b...

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Veröffentlicht in:Transplantation 1990-12, Vol.50 (6), p.1078-1081
Hauptverfasser: PEARCE, N. W, DORSCH, S. E, HALL, B. M
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Sprache:eng
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Zusammenfassung:In this study, we examined whether there was an associated change in the capacity of T cell subsets from enhanced animals with long-surviving allografts to proliferate in a PLN GVH assay. We also examined the capacity of unfractionated cells from these animals to mediate lethal GVHD, as this assay better reflects the effector phase of graft rejection (DBO).
ISSN:0041-1337
1534-6080
DOI:10.1097/00007890-199012000-00045