Routine use of cerebral protection during carotid artery stenting: results of a multicenter registry of 753 patients

To evaluate the short-term outcome of patients who underwent carotid stenting with the routine use of cerebral protection devices. In five centers, 808 successful stent procedures (of 815 attempted) were performed in 753 patients (557 [74%] men; mean [± SD] age, 70 ± 8 years). Cerebral protection involved distal filter devices (n = 640), occlusive distal balloons (n = 144), or proximal balloon protection (n = 24). The protection device was positioned successfully in 793 (98.2%) of the 808 attempted vessels. Neurologic complications occurred within 30 days after 46 procedures (5.6%), including seven major strokes, 17 minor strokes, and 22 transient ischemic attacks. There were four deaths (one following a major stroke). The 30-day incidence of stroke and death was 3.3% (27/815). The rate of stroke or death was 3.8% (8/213) for symptomatic lesions and 3.2% (19/602) for asymptomatic lesions ( P = 0.87), and 3.4% (25/729) in patients aged