Distributions of perfusion and lung water

We investigated the feasibility of using 123I-iodoantipyrine ( 123I-IAP) and 99mTc-labeled macroaggregated albumin ( 99mTc-MAA) to describe and compare the distributions of perfusion and water content in lung injuries. These radiopharmaceuticals were administered to 9 rabbits, 5 control and 4 with l...

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Veröffentlicht in:	International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology Nuclear medicine and biology, 1990, Vol.17 (6), p.561,565-563,565
Hauptverfasser:	Ekeh, Sabinus U., Chu, Robert Y.L., Ficken, Vernon J., Allen, E.William, Ryals, Carl J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antipyrine - analogs & derivatives Biological and medical sciences Extravascular Lung Water - metabolism Female In Vitro Techniques Investigative techniques, diagnostic techniques (general aspects) Iodine Radioisotopes Medical sciences Pulmonary Circulation Pulmonary Edema - diagnostic imaging Rabbits Radionuclide Imaging Technetium Tc 99m Aggregated Albumin
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Beschreibung
Zusammenfassung:	We investigated the feasibility of using 123I-iodoantipyrine ( 123I-IAP) and 99mTc-labeled macroaggregated albumin ( 99mTc-MAA) to describe and compare the distributions of perfusion and water content in lung injuries. These radiopharmaceuticals were administered to 9 rabbits, 5 control and 4 with lung injuries. Isolated lungs were imaged by a scintillation γ camera. The distribution of 123I-IAP outlined the entire lung mass whereas perfusion defect in the distribution of 99mTc-MAA was seen clearly in the case of severe lung injury.
ISSN:	0883-2897
DOI:	10.1016/0883-2897(90)90132-K