Recombinant fowlpox viruses inducing protective immunity against Newcastle disease and fowlpox viruses

The haemagglutinin-neuraminidase gene of Newcastle disease virus was inserted into a non-essential region of the fowlpox virus genome and expressed under control of the vaccinia virus 7.5 kDa polypeptide gene promoter. Immunization with the recombinant fowlpox virus elicited protective immunity in c...

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Veröffentlicht in:	Vaccine 1990-10, Vol.8 (5), p.486-490
Hauptverfasser:	Ogawa, Ryohei, Yanagida, Noboru, Saeki, Sakiko, Saito, Shuji, Ohkawa, Setsuko, Gotoh, Hiroyuki, Kodama, Kazumi, Kamogawa, Kouichi, Sawaguchi, Kazunari, Iritani, Yoshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Chickens fowlpox Fowlpox - prevention & control Fowlpox virus - genetics Fowlpox virus - immunology Fundamental and applied biological sciences. Psychology Hemagglutination Inhibition Tests Hemagglutinins, Viral - genetics Microbiology Molecular Sequence Data Neuraminidase - genetics Newcastle disease Newcastle Disease - immunology Newcastle Disease - prevention & control Newcastle disease virus Newcastle disease virus - genetics Newcastle disease virus - immunology recombinant DNA Specific Pathogen-Free Organisms Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Vaccines, Synthetic - genetics Vaccines, Synthetic - immunology Virology
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Zusammenfassung:	The haemagglutinin-neuraminidase gene of Newcastle disease virus was inserted into a non-essential region of the fowlpox virus genome and expressed under control of the vaccinia virus 7.5 kDa polypeptide gene promoter. Immunization with the recombinant fowlpox virus elicited protective immunity in chickens against both virulent Newcastle disease and fowlpox virus infection.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/0264-410X(90)90251-G