The Design of Functional DNA-Binding Proteins Based on Zinc Finger Domains

The Design of Functional DNA-Binding Proteins Based on Zinc Finger Domains

Jantz et al discuss the use of engineered zinc finger domains for the generation of biomimetic transcription factors.

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Veröffentlicht in:Chemical reviews 2004-02, Vol.104 (2), p.789-800
Hauptverfasser: Jantz, Derek, Amann, Barbara T, Gatto, Gregory J, Berg, Jeremy M
Format: Artikel
Sprache:eng
Schlagworte:
Biomimetics
Deoxyribonucleic acid
DNA
DNA - chemistry
DNA - metabolism
DNA-Binding Proteins - chemistry
Drug Design
Humans
Nucleic Acid Conformation
Proteins
Zinc
Zinc Fingers
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Zusammenfassung:Jantz et al discuss the use of engineered zinc finger domains for the generation of biomimetic transcription factors.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr020603o