Remarkable Effect of a Silicon Group on the Stereoselectivity of Radical 5-exo-Trig Cyclizations
Sulfonyl radical mediated 5-exo-trig cyclization of chiral 3-silylhepta-1,6-dienes has been shown to provide cyclopentanes having up to four stereogenic centers with an unexpectedly high level of stereocontrol.
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| Veröffentlicht in: | Organic letters 2004-02, Vol.6 (3), p.325-328 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | Sulfonyl radical mediated 5-exo-trig cyclization of chiral 3-silylhepta-1,6-dienes has been shown to provide cyclopentanes having up to four stereogenic centers with an unexpectedly high level of stereocontrol. |
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| ISSN: | 1523-7060 1523-7052 |
| DOI: | 10.1021/ol036025v |