Growth hormone response to growth hormone releasing hormone in depression and schizophrenia

Growth hormone releasing hormone, a 44-amino acid peptide (GHRH-44), was administered (1 mug/kg i.v.) to 6 normal controls, 10 schizophrenic subjects, and 7 depressed subjects. A significantly lower growth hormone (GH) response was found in the schizophrenic and depressed groups. Two molecular forms...

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Veröffentlicht in:	Psychiatry research 1990-09, Vol.33 (3), p.269-276
Hauptverfasser:	Peabody, Cecilia A., Warner, M.Dhyanne, Markoff, Edith, Hoffman, Andrew R., Wilson, Darrell M., Csernansky, John G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Depressive Disorder - blood Depressive Disorder - diagnosis Depressive Disorder - psychology Growth Hormone - blood Growth hormone releasing hormone, growth hormone, depression, schizophrenia Growth Hormone-Releasing Hormone Humans Male Middle Aged Psychiatric Status Rating Scales Schizophrenia - blood Schizophrenia - diagnosis Schizophrenic Psychology
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Beschreibung
Zusammenfassung:	Growth hormone releasing hormone, a 44-amino acid peptide (GHRH-44), was administered (1 mug/kg i.v.) to 6 normal controls, 10 schizophrenic subjects, and 7 depressed subjects. A significantly lower growth hormone (GH) response was found in the schizophrenic and depressed groups. Two molecular forms of GH, 22K GH and 20K GH, were also measured but did not further differentiate the three groups of subjects.
ISSN:	0165-1781 1872-7123
DOI:	10.1016/0165-1781(90)90043-5