High frequency of defective sperm–zona pellucida interaction in oligozoospermic infertile men

High frequency of defective sperm–zona pellucida interaction in oligozoospermic infertile men

BACKGROUND: The ability of sperm to interact with the zona pellucida (ZP) plays a critical role during the process of human fertilization. The aim of this study is to determine frequency of defective sperm–ZP interaction in oligozoospermic infertile men. METHODS: Sperm–ZP binding assays and the ZP‐i...

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Veröffentlicht in:Human reproduction (Oxford) 2004-02, Vol.19 (2), p.228-233
Hauptverfasser: Liu, De Yi, Baker, H.W.Gordon
Format: Artikel
Sprache:eng
Schlagworte:
Acrosome Reaction
Biological and medical sciences
Embryology: invertebrates and vertebrates. Teratology
Female
Fundamental and applied biological sciences. Psychology
Humans
Male
male infertility/oligozoospermia/sperm–zona pellucida interaction
Oligospermia - physiopathology
Oligospermia - therapy
Sperm Count
Sperm Injections, Intracytoplasmic
Sperm Motility
Sperm-Ovum Interactions
Spermatozoa - physiology
Zona Pellucida
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Zusammenfassung:BACKGROUND: The ability of sperm to interact with the zona pellucida (ZP) plays a critical role during the process of human fertilization. The aim of this study is to determine frequency of defective sperm–ZP interaction in oligozoospermic infertile men. METHODS: Sperm–ZP binding assays and the ZP‐induced acrosome reaction (AR) were performed in 72 infertile men with a sperm concentration
ISSN:0268-1161
1460-2350
1460-2350
DOI:10.1093/humrep/deh067