Dendritic Cells: Immunobiology and Cancer Immunotherapy

A recent workshop on “Dendritic Cells: Biology and Therapeutic Applications,” sponsored by the Juan March Foundation, brought together basic and clinical research scientists to discuss the mechanisms underlying the control of immune responses and tolerance by dendritic cells (DCs), as well as recent...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2004, Vol.20 (1), p.17-23
Hauptverfasser:	Ardavı́n, Carlos, Amigorena, Sebastián, e Sousa, Caetano Reis
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen Presentation - immunology Autoimmune diseases Cancer Cell adhesion & migration Congresses as Topic Dendritic Cells - immunology Endoplasmic reticulum Immune system Immune Tolerance - immunology Immunotherapy Lectins, C-Type - immunology Lymphocytes Neoplasms - immunology Neoplasms - pathology Neoplasms - therapy Peptides Spain T-Lymphocytes - immunology
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Zusammenfassung:	A recent workshop on “Dendritic Cells: Biology and Therapeutic Applications,” sponsored by the Juan March Foundation, brought together basic and clinical research scientists to discuss the mechanisms underlying the control of immune responses and tolerance by dendritic cells (DCs), as well as recent research in cancer immunotherapy based on DC vaccination. Particular emphasis was placed on antigen processing and presentation by DCs, C-type lectin antigen receptors, DC maturation and polarization of T cell responses, the control of immunity versus tolerance by DCs, the developmental origin of DCs, and the use of DCs in cancer immunotherapy.
ISSN:	1074-7613 1097-4180
DOI:	10.1016/S1074-7613(03)00352-2