Electrochemical determination of oxytetracycline in veterinary drugs

Conductometric, potentiometric and cyclic voltammetric (CV) titration methods are proposed for determination of oxytetracycline (OTC), commonly used in veterinary. The electrochemical titration of OTC hydrochloride with NH 4Mo 7O 24, NaVO 3, NaOH, AgNO 3 and FeCl 3 as titrants are reported. The prop...

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Veröffentlicht in:Journal of pharmaceutical and biomedical analysis 2004-01, Vol.34 (1), p.95-102
Hauptverfasser: Kurzawa, Marzanna, Kowalczyk-Marzec, Agnieszka
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container_title Journal of pharmaceutical and biomedical analysis
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creator Kurzawa, Marzanna
Kowalczyk-Marzec, Agnieszka
description Conductometric, potentiometric and cyclic voltammetric (CV) titration methods are proposed for determination of oxytetracycline (OTC), commonly used in veterinary. The electrochemical titration of OTC hydrochloride with NH 4Mo 7O 24, NaVO 3, NaOH, AgNO 3 and FeCl 3 as titrants are reported. The proposed methods were found to be highly precise, having a relative standard deviation (R.S.D.) below 1.0%. Proposed electrochemical titrations were successfully applied to the assay of commercial preparations: Tetrox, Tetramutin ®OT and Neox, containing the above-mentioned antibiotics. The validity of the methods was tested by the recovery studies of standard addition to pharmaceuticals and results were found to be satisfactory.
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The electrochemical titration of OTC hydrochloride with NH 4Mo 7O 24, NaVO 3, NaOH, AgNO 3 and FeCl 3 as titrants are reported. The proposed methods were found to be highly precise, having a relative standard deviation (R.S.D.) below 1.0%. Proposed electrochemical titrations were successfully applied to the assay of commercial preparations: Tetrox, Tetramutin ®OT and Neox, containing the above-mentioned antibiotics. 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subjects Analysis
Analytical, structural and metabolic biochemistry
Biological and medical sciences
Conductometry
Cyclic
Electrochemistry - methods
Fundamental and applied biological sciences. Psychology
General pharmacology
Medical sciences
Oxytetracycline - analysis
Oxytetracycline - chemistry
Oxytetracycline hydrochloride
Pharmacology. Drug treatments
Potentiometry
Titrimetric assay
Veterinary Drugs - analysis
Veterinary Drugs - chemistry
Voltammetry
title Electrochemical determination of oxytetracycline in veterinary drugs
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