Evaluation of 3H-Paroxetine as a Radioligand for in vivo Study of 5-Hydroxytryptamine Uptake Sites in Mouse Brain

The distribution of radioactivity in the mouse brain after intravenous administration of 3H-paroxetine was in the order (highest to lowest) hypothalamus>cerebral cortex>cerebellum. The radioactivity in the hypothalamus and cerebral cortex after injection of 3H-paroxetine was significantly decr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	RADIOISOTOPES 1990/08/15, Vol.39(8), pp.335-341
Hauptverfasser:	HASHIMOTO, Kenji, GOROMARU, Tsuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	5-hydroxytryptamine uptake sites Animals Binding Sites Brain - metabolism Evaluation Studies as Topic in vivo binding Injections, Intravenous Male Mice mouse brain Paroxetine Piperidines - administration & dosage Piperidines - pharmacokinetics Radioligand Assay Receptors, Serotonin - metabolism Serotonin Antagonists - administration & dosage Serotonin Antagonists - pharmacokinetics Tritium - administration & dosage tritium-paroxetine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!