Cost-utility analysis for endoscopic sinus surgery

To undertake cost-utility analysis for endoscopic sinus surgery (ESS) in order to analyze the cost-effectiveness of different chronic sinusitis severity groups. One hundred ninety-two patients with chronic sinusitis were evaluated with a Chronic Sinusitis Survey (CSS) before and 1-year after ESS. Direct health care cost data during the first year after operation were retrieved. The utility gain is defined as change in the CSS total score. The cost-utility ratio was defined as cost per utility gain. Patients are stratified by disease severity using the Harvard Staging System. The average total direct cost attributable to ESS is NT $40,829 in the first postoperative year and the average cost-utility ratio is NT $2194.42. The high cost-utility ratio of NT $3246.45 for pansinusitis cases is due to the higher cost and limited utility gain. Treating mild and moderate chronic sinusitis are most cost-effective because of their favorable utility gain and relatively reasonable cost. However, there is no proportional linear relationship between disease severity and cost-utility ratio.