GABAA type binding sites on membranes of spermatozoa
The binding of [3H] gamma-aminobutyric acid (GABA) to seminal membranes of swines and rams was examined. Specific, GABA binding was demonstrated in both species, which showed the features of GABAA type receptors. The affinity of binding was similar in both species, whereas the density of seminal GAB...
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| Veröffentlicht in: | Life sciences (1973) 1990, Vol.47 (13), p.1147-1151 |
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| container_title | Life sciences (1973) |
| container_volume | 47 |
| creator | ERDOÊ, S. L WEKERLE, L |
| description | The binding of [3H] gamma-aminobutyric acid (GABA) to seminal membranes of swines and rams was examined. Specific, GABA binding was demonstrated in both species, which showed the features of GABAA type receptors. The affinity of binding was similar in both species, whereas the density of seminal GABA binding sites was 5 times higher in swine. Our findings suggest that GABA may have a direct effect on spermatozoa. |
| doi_str_mv | 10.1016/0024-3205(90)90175-Q |
| format | Article |
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L ; WEKERLE, L</creator><creatorcontrib>ERDOÊ, S. L ; WEKERLE, L</creatorcontrib><description>The binding of [3H] gamma-aminobutyric acid (GABA) to seminal membranes of swines and rams was examined. Specific, GABA binding was demonstrated in both species, which showed the features of GABAA type receptors. The affinity of binding was similar in both species, whereas the density of seminal GABA binding sites was 5 times higher in swine. Our findings suggest that GABA may have a direct effect on spermatozoa.</description><identifier>ISSN: 0024-3205</identifier><identifier>EISSN: 1879-0631</identifier><identifier>DOI: 10.1016/0024-3205(90)90175-Q</identifier><identifier>PMID: 2172681</identifier><identifier>CODEN: LIFSAK</identifier><language>eng</language><publisher>Amsterdam: Elsevier</publisher><subject>Animals ; Binding Sites ; Biological and medical sciences ; Cell Membrane - metabolism ; Fundamental and applied biological sciences. 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L</creatorcontrib><creatorcontrib>WEKERLE, L</creatorcontrib><title>GABAA type binding sites on membranes of spermatozoa</title><title>Life sciences (1973)</title><addtitle>Life Sci</addtitle><description>The binding of [3H] gamma-aminobutyric acid (GABA) to seminal membranes of swines and rams was examined. Specific, GABA binding was demonstrated in both species, which showed the features of GABAA type receptors. The affinity of binding was similar in both species, whereas the density of seminal GABA binding sites was 5 times higher in swine. Our findings suggest that GABA may have a direct effect on spermatozoa.</description><subject>Animals</subject><subject>Binding Sites</subject><subject>Biological and medical sciences</subject><subject>Cell Membrane - metabolism</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>gamma-Aminobutyric Acid - metabolism</subject><subject>Male</subject><subject>Mammalian male genital system</subject><subject>Morphology. Physiology</subject><subject>Receptors, GABA-A - metabolism</subject><subject>Sheep</subject><subject>Spermatozoa - metabolism</subject><subject>Swine</subject><subject>Vertebrates: reproduction</subject><issn>0024-3205</issn><issn>1879-0631</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkF1LwzAUhoMoc07_gUJvFL2onpOkTXJZh05hIAO9DmmbSKVfNt3F_PW2rsyrw8v7weEh5BLhHgHjBwDKQ0YhulVwpwBFFG6OyBylUCHEDI_J_BA5JWfefwFAFAk2IzOKgsYS54SvksckCfpda4O0qPOi_gx80VsfNHVQ2SrtTD0KF_jWdpXpm5_GnJMTZ0pvL6a7IB_PT-_Ll3D9tnpdJuswo1z0YRrlIITLKaBkJpd5FnE0IC3EghkRq8hwlWaKo6OUilRJx8EaE4vUMYmCLcjNfrftmu-t9b2uCp_Zshx-arZeSwAVAcMhyPfBrGu876zTbVdUpttpBD3C0iMJPZLQCvQfLL0ZalfT_jatbH4oTXQG_3ryjc9M6QYWWeH_txVnECOyX067b6A</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>ERDOÊ, S. 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Psychology</topic><topic>gamma-Aminobutyric Acid - metabolism</topic><topic>Male</topic><topic>Mammalian male genital system</topic><topic>Morphology. Physiology</topic><topic>Receptors, GABA-A - metabolism</topic><topic>Sheep</topic><topic>Spermatozoa - metabolism</topic><topic>Swine</topic><topic>Vertebrates: reproduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ERDOÊ, S. L</creatorcontrib><creatorcontrib>WEKERLE, L</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Life sciences (1973)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ERDOÊ, S. L</au><au>WEKERLE, L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>GABAA type binding sites on membranes of spermatozoa</atitle><jtitle>Life sciences (1973)</jtitle><addtitle>Life Sci</addtitle><date>1990</date><risdate>1990</risdate><volume>47</volume><issue>13</issue><spage>1147</spage><epage>1151</epage><pages>1147-1151</pages><issn>0024-3205</issn><eissn>1879-0631</eissn><coden>LIFSAK</coden><abstract>The binding of [3H] gamma-aminobutyric acid (GABA) to seminal membranes of swines and rams was examined. Specific, GABA binding was demonstrated in both species, which showed the features of GABAA type receptors. The affinity of binding was similar in both species, whereas the density of seminal GABA binding sites was 5 times higher in swine. Our findings suggest that GABA may have a direct effect on spermatozoa.</abstract><cop>Amsterdam</cop><pub>Elsevier</pub><pmid>2172681</pmid><doi>10.1016/0024-3205(90)90175-Q</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0024-3205 |
| ispartof | Life sciences (1973), 1990, Vol.47 (13), p.1147-1151 |
| issn | 0024-3205 1879-0631 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80095031 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Binding Sites Biological and medical sciences Cell Membrane - metabolism Fundamental and applied biological sciences. Psychology gamma-Aminobutyric Acid - metabolism Male Mammalian male genital system Morphology. Physiology Receptors, GABA-A - metabolism Sheep Spermatozoa - metabolism Swine Vertebrates: reproduction |
| title | GABAA type binding sites on membranes of spermatozoa |
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