The classification of glomerulonephritis in systemic lupus erythematosus revisited

The classification of glomerulonephritis in systemic lupus erythematosus revisited.The currently used classification reflects our understanding of the pathogenesis of the various forms of lupus nephritis, but clinicopathologic studies have revealed the need for improved categorization and terminolog...

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Veröffentlicht in:Kidney international 2004-02, Vol.65 (2), p.521-530
Hauptverfasser: Weening, Jan J., D'agati, Vivette D., Schwartz, Melvin M., Seshan, Surya V., Alpers, Charles E., Appel, Gerald B., Balow, James E., Bruijn, J.A.N. A., Cook, Terence, Ferrario, Franco, Fogo, Agnes B., Ginzler, Ellen M., Hebert, Lee, Hill, Gary, Hill, Prue, Jennette, J. Charles, Kong, Norella C., Lesavre, Philippe, Lockshin, Michael, Looi, Lai-Meng, Makino, Hirofumi, Moura, Luiz A., Nagata, Michio, ON Behalf of the International Society of Nephrology and Renal Pathology Society Working Group on the Classification Oflupus Nephritis
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Sprache:eng
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Zusammenfassung:The classification of glomerulonephritis in systemic lupus erythematosus revisited.The currently used classification reflects our understanding of the pathogenesis of the various forms of lupus nephritis, but clinicopathologic studies have revealed the need for improved categorization and terminology. Based on the 1982 classification published under the auspices of the World Health Organization (WHO) and subsequent clinicopathologic data, we propose that class I and II be used for purely mesangial involvement (I, mesangial immune deposits without mesangial hypercellularity; II, mesangial immune deposits with mesangial hypercellularity); class III for focal glomerulonephritis (involving
ISSN:0085-2538
1523-1755
DOI:10.1111/j.1523-1755.2004.00443.x