Visual function more than 10 years after optic neuritis: experience of the optic neuritis treatment trial

To assess visual function more than 10 years after an episode of optic neuritis in patients enrolled in the Optic Neuritis Treatment Trial. Longitudinal follow-up of a randomized clinical trial. Vision testing included measures of visual acuity, contrast sensitivity, and visual field. Quality of life was assessed with the National Eye Institute Visual Function Questionnaire. Examinations were completed on 319 patients. In most patients, visual function test results in the eyes that experienced optic neuritis at study entry (“affected eyes”) were normal or only slightly abnormal after 9.9 to 13.7 years. Visual acuity in the affected eyes was ≥20/20 in 74%, 20/25 to 20/40 in 18%,