Adenoviral Infections in Children: The Impact of Rapid Diagnosis

Adenovirus (ADV) infections were difficult to diagnose in the past, and many infections were unrecognized. Direct fluorescent assay (DFA) for the rapid diagnosis of ADV infection, as part of a viral respiratory panel, became available at Primary Children's Medical Center (Salt Lake City, UT) in...

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Veröffentlicht in:Pediatrics (Evanston) 2004-01, Vol.113 (1), p.e51-e56
Hauptverfasser: Rocholl, Christian, Gerber, Kris, Daly, Judy, Pavia, Andrew T, Byington, Carrie L
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Sprache:eng
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Zusammenfassung:Adenovirus (ADV) infections were difficult to diagnose in the past, and many infections were unrecognized. Direct fluorescent assay (DFA) for the rapid diagnosis of ADV infection, as part of a viral respiratory panel, became available at Primary Children's Medical Center (Salt Lake City, UT) in December 2000. To describe children with ADV infection diagnosed by DFA and viral culture and document the impact of rapid ADV testing on patient care. DFA testing for respiratory viruses including ADV was performed on nasal wash specimens with parallel viral culture. Chart review was performed for all ADV-positive patients identified from microbiology records between December 2000 and May 2002. Of 1901 patients positive for respiratory viruses, 143 (7.5%) were ADV-positive by DFA or culture. The mean age of ADV-positive children was 23 months; 90% were
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.113.1.e51