A randomised trial comparing low dose vaginal misoprostol and dinoprostone for labour induction

Objective To compare vaginal misoprostol with dinoprostone for induction of labour. Design Randomised multicentre trial. Setting Labour wards of one university hospital and two teaching hospitals. Population Six hundred and eighty‐one women with indication for labour induction at ≥36 weeks of gestation, singleton pregnancy and no previous ceasarean section. Methods Misoprostol (25 mcg, hospital‐prepared capsule) in the posterior vaginal fornix, every four hours, maximum three times daily or dinoprostone gel (1 mg) every four hours. Oxytocin was administered if necessary. Main outcome measures Primary: ‘adverse neonatal outcome’ (5‐minute Apgar score