Leukocyte depletion filters: A comparison of efficiency

Four commercially available leukocyte depletion filters were evaluated using a flow cytometric technique to determine the efficiency of each type of filter. The Sepacell R‐500A® and the PALL RC50® were the most efficient in leukocyte depletion having a mean depletion percentage of 99.3% and 99.5%, r...

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Veröffentlicht in:	American journal of hematology 1990-11, Vol.35 (3), p.184-186
1. Verfasser:	Bodensteiner, David C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Transfusion Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Cell Separation - methods Erythrocyte Count Erythrocytes - cytology filter Filtration - methods flow cytometric technique Humans Leukocyte Count Leukocytes - cytology Medical sciences platelet alloimmunization Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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Zusammenfassung:	Four commercially available leukocyte depletion filters were evaluated using a flow cytometric technique to determine the efficiency of each type of filter. The Sepacell R‐500A® and the PALL RC50® were the most efficient in leukocyte depletion having a mean depletion percentage of 99.3% and 99.5%, respectively. The PALL RC100® which is used for two units also had a 99.3% depletion with the first unit but with the second unit the depletion dropped to 94.2%. The Imugard IG‐500® had a 97.3% depletion. Red cell recovery ranged from 87.4% for the PALL RC50® to 92.2% for the Sepacell R‐500A®.
ISSN:	0361-8609 1096-8652
DOI:	10.1002/ajh.2830350308