Activin A and inhibin B in extra-embryonic coelomic and amniotic fluids, and maternal serum in early pregnancy

Activin A and inhibin B in extra-embryonic coelomic and amniotic fluids, and maternal serum in early pregnancy

Activin A and inhibin B levels were measured, using a two-site enzyme immunoassay, in extra-embryonic coelomic fluid, amniotic fluid and maternal serum samples retrieved from 23 healthy pregnant women, at 8 ( n=8), 9 ( n=8), and 10 ( n=7) weeks of gestation. Dimeric activin A and inhibin B were meas...

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Veröffentlicht in:Placenta (Eastbourne) 1998-07, Vol.19 (5), p.435-438
Hauptverfasser: Luisi, S., Battaglia, C., Florio, P., D'Ambrogio, G., Taponeco, F., Santuz, M., Genazzani, A.R., Petraglia, F.
Format: Artikel
Sprache:eng
Schlagworte:
Activins
Adult
Amniotic Fluid - metabolism
Biological and medical sciences
Body Fluids - metabolism
Embryo, Mammalian - metabolism
Female
Fundamental and applied biological sciences. Psychology
Humans
Immunoenzyme Techniques
Inhibins - metabolism
Mother. Fetoplacental unit. Mammary gland. Milk
Pregnancy - blood
Pregnancy Trimester, First
Pregnancy. Parturition. Lactation
Vertebrates: reproduction
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Zusammenfassung:Activin A and inhibin B levels were measured, using a two-site enzyme immunoassay, in extra-embryonic coelomic fluid, amniotic fluid and maternal serum samples retrieved from 23 healthy pregnant women, at 8 ( n=8), 9 ( n=8), and 10 ( n=7) weeks of gestation. Dimeric activin A and inhibin B were measurable in all samples. Median (± sem) activin A concentrations in coelomic fluid (0.98 ± 0.34 ng/ml) were significantly higher than in maternal serum (0.68 ± 0.05 ng/ml) and in amniotic fluid (0.09 ± 0.04 ng/ml) ( P
ISSN:0143-4004
1532-3102
DOI:10.1016/S0143-4004(98)90085-6