Evaluation of a rough mutant of Brucella melitensis in pregnant goats

Evaluation of a rough mutant of Brucella melitensis in pregnant goats

Brucella melitensis strain VTRM1, a rough derivative of B melitensis strain 16M, is able to colonise the lymph nodes of goats, does not induce abortion in pregnant goats when used at doses leading to abortions with virulent strain 16M, and does not induce anti-O chain antibodies. However, strain VTR...

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Veröffentlicht in:Research in veterinary science 1998-05, Vol.64 (3), p.259-260
Hauptverfasser: Elzer, P.H., Enright, F.M., McQuiston, J.R., Boyle, S.M., Schurig, G.G.
Format: Artikel
Sprache:eng
Schlagworte:
Abortion, Veterinary - microbiology
Animals
Antibodies, Bacterial - biosynthesis
Brucella melitensis - genetics
Brucella melitensis - pathogenicity
Brucellosis - immunology
Brucellosis - physiopathology
Brucellosis - veterinary
Female
Goat Diseases - immunology
Goat Diseases - microbiology
Goat Diseases - physiopathology
Goats
Pregnancy
Species Specificity
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Zusammenfassung:Brucella melitensis strain VTRM1, a rough derivative of B melitensis strain 16M, is able to colonise the lymph nodes of goats, does not induce abortion in pregnant goats when used at doses leading to abortions with virulent strain 16M, and does not induce anti-O chain antibodies. However, strain VTRM1 as a single dose vaccine induces only partial protection against both infection and abortion following challenge.
ISSN:0034-5288
1532-2661
DOI:10.1016/S0034-5288(98)90135-7