Diffusion-limited Reaction of Free Nitric Oxide with Erythrocytes

Diffusion-limited Reaction of Free Nitric Oxide with Erythrocytes

Concentration changes of nitric oxide (NO) were monitored using an NO-sensitive electrode in phosphate-buffered saline (PBS) with either free oxyhemoglobin (oxyHb) or red blood cells (RBCs). In aerated PBS, the half-life of 0.9 μ m NO is greater than 4 min. NO is undetectable (

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Veröffentlicht in:The Journal of biological chemistry 1998-07, Vol.273 (30), p.18709-18713
Hauptverfasser: Liu, X, Miller, M J, Joshi, M S, Sadowska-Krowicka, H, Clark, D A, Lancaster, Jr, J R
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Diffusion
Electrochemistry
Erythrocytes - metabolism
Hemoglobins - metabolism
In Vitro Techniques
Models, Chemical
Nitric Oxide - metabolism
Oxyhemoglobins - metabolism
Rats
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Zusammenfassung:Concentration changes of nitric oxide (NO) were monitored using an NO-sensitive electrode in phosphate-buffered saline (PBS) with either free oxyhemoglobin (oxyHb) or red blood cells (RBCs). In aerated PBS, the half-life of 0.9 μ m NO is greater than 4 min. NO is undetectable (
ISSN:0021-9258
1083-351X
DOI:10.1074/jbc.273.30.18709