Multiple Forms of GnRH Are Released from Perifused Medial Basal Hypothalamic/Preoptic Area (MBH/POA) Explants in Birds

Both chicken gonadotropin-releasing hormones I and II (cGnRH I and II) were detected in abundant quantity by radioimmunoassay of extracts of Japanese quail medial basal hypothalamic/preoptic area (MBH/POA) fragments that included the median eminence (ME) region. However, in radioimmunoassayed extrac...

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Veröffentlicht in:	General and comparative endocrinology 1998-07, Vol.111 (1), p.95-101
Hauptverfasser:	Millam, J.R., Ottinger, M.A., Craig-Veit, C.B., Fan, Y., Chaiseha, Y., El Halawani, M.E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals chicken gonadotropin-releasing hormone I chicken gonadotropin-releasing hormone II Coturnix - metabolism Female Gonadotropin-Releasing Hormone - analogs & derivatives Gonadotropin-Releasing Hormone - analysis Gonadotropin-Releasing Hormone - metabolism Hypothalamus, Middle - chemistry Hypothalamus, Middle - drug effects Hypothalamus, Middle - metabolism In Vitro Techniques in vitroperifusion Japanese quail Male Norepinephrine - pharmacology Preoptic Area - chemistry Preoptic Area - drug effects Preoptic Area - metabolism Pyrrolidonecarboxylic Acid - analogs & derivatives turkey Turkeys - metabolism
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Zusammenfassung:	Both chicken gonadotropin-releasing hormones I and II (cGnRH I and II) were detected in abundant quantity by radioimmunoassay of extracts of Japanese quail medial basal hypothalamic/preoptic area (MBH/POA) fragments that included the median eminence (ME) region. However, in radioimmunoassayed extracts of Japanese quail ME alone, the concentration of cGnRH I greatly exceeded that of cGnRH II (≈450 pg/ME vs
ISSN:	0016-6480 1095-6840
DOI:	10.1006/gcen.1998.7094