Identification of prostaglandin E2 and leukotriene B4 in the synovial fluid of painful, dysfunctional temporomandibular joints

It has been hypothesized that prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) should be present in the synovial fluid of inflamed, dysfunctional temporomandibular joints. An assay to identify PGE2 and LTB4 and platelet-activating factor (PAF) was used, and a strong correlation between the levels o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of oral and maxillofacial surgery 1990-09, Vol.48 (9), p.968-971
Hauptverfasser:	QUINN, J. H, BAZAN, N. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cartilage, Articular - immunology Dentistry Dinoprostone - analysis Facial bones, jaws, teeth, parodontium: diseases, semeiology Female Humans Joint Dislocations - immunology Leukotriene B4 - analysis Male Medical sciences Non tumoral diseases Otorhinolaryngology. Stomatology Platelet Activating Factor - analysis Synovial Fluid - immunology Synovitis - immunology Synovitis - pathology Temporomandibular Joint Dysfunction Syndrome - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	It has been hypothesized that prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) should be present in the synovial fluid of inflamed, dysfunctional temporomandibular joints. An assay to identify PGE2 and LTB4 and platelet-activating factor (PAF) was used, and a strong correlation between the levels of these lipid mediators of pain and inflammation and an index of clinical joint pathology was found.
ISSN:	0278-2391 1531-5053
DOI:	10.1016/0278-2391(90)90011-p