Purification of art v I, a relevant allergen of Artemisia vulgaris pollen

An allergenic protein from Artemisia vulgaris pollen has been purified to homogeneity. Its molecular weight in native conditions is 47,000. The purified allergen, hereafter denominated Art v I, is a monomeric protein. It is a clinically relevant allergen since, at least, 70% of the individuals aller...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular immunology 1990-07, Vol.27 (7), p.651-657
Hauptverfasser:	de la Hoz, Francisco, Polo, Florentino, del Prado, Jaime Moscoso, Sellés, Javier G., Lombardero, Manuel, Carreira, José
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Allergens - isolation & purification Blotting, Western Chemical Precipitation Humans Immunoblotting Immunoelectrophoresis Immunoelectrophoresis, Two-Dimensional Immunoglobulin E - immunology Isoelectric Point Molecular Weight Plant Proteins - immunology Plant Proteins - isolation & purification Plants - immunology Pollen - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	An allergenic protein from Artemisia vulgaris pollen has been purified to homogeneity. Its molecular weight in native conditions is 47,000. The purified allergen, hereafter denominated Art v I, is a monomeric protein. It is a clinically relevant allergen since, at least, 70% of the individuals allergic to Artemisia vulgaris pollen have specific IgE in serum and in mast cells, demonstrated by ELISA and skin prick tests, respectively.
ISSN:	0161-5890 1872-9142
DOI:	10.1016/0161-5890(90)90008-N