New Ceramide from Marine Sponge Haliclona koremella and Related Compounds as Antifouling Substances against Macroalgae

A new ceramide N-docosanoyl-d-erythro-(2S,3R)-16-methyl-heptadecasphing-4(E)-enine (C22 ceramide) was isolated from the marine sponge Haliclona koremella as an antifouling substance against macroalgae. The structure of this substance was elucidated by spectral means. Antifouling activity of several...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1998-06, Vol.61 (6), p.823-826
Hauptverfasser:	Hattori, Tadamasa, Adachi, Kyoko, Shizuri, Yoshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	AMIDAS AMIDE AMIDES Analytical, structural and metabolic biochemistry Animals ANTIFOULING AGENTS BELAU Biological and medical sciences Ceramides - isolation & purification Ceramides - pharmacology CHEMICAL COMPOSITION CHEMICAL STRUCTURE COMPOSICION QUIMICA COMPOSITION CHIMIQUE EPONGE ESPECTROMETRIA ESPONJAS ESTRUCTURA QUIMICA Eukaryota - drug effects Eukaryota - genetics Fundamental and applied biological sciences. Psychology Lipids Magnetic Resonance Spectroscopy Mass Spectrometry OCEANIA OCEANIE Other biological molecules PARAZOA Porifera - chemistry SPECTRAL ANALYSIS SPECTROMETRIE SPECTROMETRY Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Sphingolipids SPONGES STRUCTURE CHIMIQUE ULVA CONGLOBATA
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Zusammenfassung:	A new ceramide N-docosanoyl-d-erythro-(2S,3R)-16-methyl-heptadecasphing-4(E)-enine (C22 ceramide) was isolated from the marine sponge Haliclona koremella as an antifouling substance against macroalgae. The structure of this substance was elucidated by spectral means. Antifouling activity of several related compounds was also examined.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np970527y