PRADIMICINS A, B AND C: NEW ANTIFUNGAL ANTIBIOTICS: I. TAXONOMY, PRODUCTION, ISOLATION AND PHYSICO-CHEMICAL PROPERTIES

PRADIMICINS A, B AND C: NEW ANTIFUNGAL ANTIBIOTICS: I. TAXONOMY, PRODUCTION, ISOLATION AND PHYSICO-CHEMICAL PROPERTIES

New antifungal antibiotics, pradimicins A, B and C were isolated from the culture broth of actinomycete strains proposed as Actinomadura hibisca. They are orange to red pigments containing a benzo[a]naphthacenequinone chromophore substituted with a D-alanine, an aminosugar and a D-xylose (pradimicin...

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Veröffentlicht in:Journal of antibiotics 1990/07/25, Vol.43(7), pp.755-762
Hauptverfasser: TOMITA, KOJI, NISHIO, MAKI, SAITOH, KYOICHIRO, YAMAMOTO, HARUAKI, HOSHINO, YUTAKA, OHKUMA, HIROAKI, KONISHI, MASATAKA, MIYAKI, TAKEO, OKI, TOSHIKAZU
Format: Artikel
Sprache:eng
Schlagworte:
Actinomycetales - classification
Actinomycetales - growth & development
Actinomycetales - metabolism
Actinomycetales - ultrastructure
Anthracyclines
Antibiotics (antibacterial agents, antifungal agents)
Antibiotics, Antineoplastic - analysis
Antibiotics, Antineoplastic - biosynthesis
Antibiotics, Antineoplastic - isolation & purification
Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents
Antifungal Agents - analysis
Antifungal Agents - biosynthesis
Antifungal Agents - isolation & purification
Applied microbiology
Biological and medical sciences
Chromatography, High Pressure Liquid
Crystallization
Fermentation
Fundamental and applied biological sciences. Psychology
Magnetic Resonance Spectroscopy
Microbiology
Microscopy, Electron
Microscopy, Electron, Scanning
Molecular Structure
Soil Microbiology
Spectrophotometry, Infrared
Spectrophotometry, Ultraviolet
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Zusammenfassung:New antifungal antibiotics, pradimicins A, B and C were isolated from the culture broth of actinomycete strains proposed as Actinomadura hibisca. They are orange to red pigments containing a benzo[a]naphthacenequinone chromophore substituted with a D-alanine, an aminosugar and a D-xylose (pradimicins A and C).
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.43.755