Effects of 6- N-propyl-2-thiouracil on growth, hormonal profiles, carcass and reproductive traits of boars

Effects of 6- N-propyl-2-thiouracil on growth, hormonal profiles, carcass and reproductive traits of boars

Neonatal 6- N-propyl-2-thiouracil (PTU)-induced hypothyroidism reduces body weight but increases testicular size in adult male rodents. The objective of this study was to determine the effect of prepubertal PTU treatment on boars. For Experiment I, boars ( n=28) were randomly allotted to eight pens....

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Veröffentlicht in:Animal reproduction science 1998-02, Vol.50 (1), p.81-94
Hauptverfasser: Tarn, C.Y, Rosenkrans, C.F, Apple, J.K, Kirby, J.D
Format: Artikel
Sprache:eng
Schlagworte:
Aging
Animals
Body Composition - drug effects
Body Temperature
Body Weight - drug effects
Carcass quality
Eating
Estradiol - blood
Follicle Stimulating Hormone - blood
Growth - drug effects
Hormones - blood
Hypothyroidism
Male
Pig—male reproduction
Propylthiouracil - administration & dosage
Propylthiouracil - pharmacology
Reproduction - drug effects
Sperm Count
Swine
Testosterone - blood
Thyroxine - blood
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Zusammenfassung:Neonatal 6- N-propyl-2-thiouracil (PTU)-induced hypothyroidism reduces body weight but increases testicular size in adult male rodents. The objective of this study was to determine the effect of prepubertal PTU treatment on boars. For Experiment I, boars ( n=28) were randomly allotted to eight pens. Each pen received one of four PTU doses (0, 0.01, 0.03 and 0.1% in a basal diet) between 28 and 56 days of age (DOA). Due to a lack of difference among three PTU treatments, PTU-treated boars were pooled. Boars treated with PTU had lower ( P
ISSN:0378-4320
1873-2232
DOI:10.1016/S0378-4320(97)00091-2