Cytotoxic compounds from the roots of Juglans mandshurica

Three new compounds, a diarylheptanone glucoside (1), 4,5, 8-trihydroxy-alpha-tetralone 5-O-beta-d-[6'-O-(3", 5"-dimethoxy-4"-hydroxybenzoyl)]glucopyranoside (2), and 1,4, 8-trihydroxy-3-naphthalenecarboxylic acid 1-O-beta-d-glucopyranoside methyl ester (3), were isolated from th...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1998-05, Vol.61 (5), p.643-645
Hauptverfasser:	Kim, S.H, Lee, K.S, Son, J.K, Je, G.H, Lee, J.S, Lee, C.H, Cheong, C.J
Format:	Artikel
Sprache:	eng
Schlagworte:	AGENTES ANTINEOPLASTICOS ANTINEOPLASTIC AGENTS Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Biological and medical sciences Bridged-Ring Compounds - chemistry Bridged-Ring Compounds - isolation & purification CARCINOMA CARCINOME CHEMICAL COMPOSITION CHEMICAL STRUCTURE COLON COMPOSICION QUIMICA COMPOSITION CHIMIQUE Diarylheptanoids DRUG PLANTS Drug Screening Assays, Antitumor ENFERMEDADES INTESTINALES ESPECTROMETRIA ESTRUCTURA QUIMICA General pharmacology GENERO HUMANO GENRE HUMAIN GLUCOSIDE GLUCOSIDES Glucosides - chemistry Glucosides - isolation & purification GLUCOSIDOS HEPTANE HIDROCARBUROS Humans HYDROCARBONS HYDROCARBURE INTESTIN INTESTINAL DISEASES INTESTINES INTESTINOS JUGLANS KOREA REPUBLIC LUNG CANCER MALADIE INTESTINALE MANKIND Medical sciences MEDICAMENT CYTOSTATIQUE Naphthalenes - chemistry Naphthalenes - isolation & purification NEOPLASMAS NEOPLASME NEOPLASMS Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Roots - chemistry PLANTAS MEDICINALES PLANTE MEDICINALE Plants, Medicinal - chemistry RACINE RAICES REPUBLICA DE COREA REPUBLIQUE DE COREE ROOTS SPECTRAL ANALYSIS SPECTROMETRIE SPECTROMETRY Spectrum Analysis STRUCTURE CHIMIQUE SUBSTANCE TOXIQUE SUSTANCIAS TOXICAS Tetralones TOXIC SUBSTANCES Tumor Cells, Cultured
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Beschreibung
Zusammenfassung:	Three new compounds, a diarylheptanone glucoside (1), 4,5, 8-trihydroxy-alpha-tetralone 5-O-beta-d-[6'-O-(3", 5"-dimethoxy-4"-hydroxybenzoyl)]glucopyranoside (2), and 1,4, 8-trihydroxy-3-naphthalenecarboxylic acid 1-O-beta-d-glucopyranoside methyl ester (3), were isolated from the roots of Juglans mandshurica, and their structures were elucidated on the basis of spectroscopic studies including 2D-NMR.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np970413m