Diagnosis of Trisomy 18 Using Spontaneously Dividing Cells from Fetal Umbilical Cord Blood: A Novel Approach for Rapid Late Second and Third Trimester Prenatal Diagnosis

ABSTRACT Cytogenetic methodology recently developed by us allows spontaneously dividing cells in fetal cord blood to be used for rapid (24 hours) chromosome analysis. We utilized this methodology to diagnose trisomy 18 and facilitate clinical management in a 32-week pregnancy characterized by multip...

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Veröffentlicht in:	American journal of perinatology 1990-07, Vol.7 (3), p.211-213
Hauptverfasser:	Tharapel, Avirachan T., Moretti, Michael L., Meyers, Carole M., Shulman, Lee P., Tipton, Robert E., Summitt, John B., Elias, Sherman, Wilroy, R. Sid, Epps, Michael, Simpson, Joe Leigh
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Multiple - diagnosis Adult Chromosomes, Human, Pair 18 Female Fetal Blood - cytology Fetal Growth Retardation - diagnosis Humans ORIGINAL ARTICLE Pregnancy Pregnancy Trimester, Second Pregnancy Trimester, Third Prenatal Diagnosis - methods Trisomy
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