Isolation and Characterization of a New Pyrano[4′, 3′:6, 7]naphtho[1, 2-b]xanthene Antibiotic FD-594

During our screening of microbial metabolites for effective drugs against tumor cell lines, we discovered a new pyrano[4′, 3′:6, 7]naphtho[1, 2-b]xanthene derivative, FD-594 from the fermentation broth of Streptomyces sp. TA-0256. FD-594 shows moderate activity against tumor cell lines, comparative...

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