Actinic prurigo among the Chimila Indians in Colombia: HLA studies

The Chimila, a Colombian Amerindian group that lives at a low altitude, have a high incidence of actinic prurigo. We present the human lymphocyte antigen (HLA) findings of 43 Chimilas with the disease and of 62 control subjects and show an association of actinic prurigo with the Cw4 antigen.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Academy of Dermatology 1990-06, Vol.22 (6), p.1049-1051
Hauptverfasser:	Bernal, J.E., Duran de Rueda, Maria Melida, Ordonez, Clara Patricia, Duran, Clemencia, de Brigard, Delia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Colombia Dermatology Female Hereditary diseases of the skin. Congenital diseases of the skin. Haemangioma of the skin, of mucosae and of soft tissue HLA Antigens - analysis Humans Indians, South American Male Medical sciences Pedigree Prurigo - genetics Prurigo - immunology Tropical medicine Ultraviolet Rays - adverse effects
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Beschreibung
Zusammenfassung:	The Chimila, a Colombian Amerindian group that lives at a low altitude, have a high incidence of actinic prurigo. We present the human lymphocyte antigen (HLA) findings of 43 Chimilas with the disease and of 62 control subjects and show an association of actinic prurigo with the Cw4 antigen.
ISSN:	0190-9622 1097-6787
DOI:	10.1016/0190-9622(90)70150-G