Luteal function associated with single, multiple and ectopic embryo implantation in natural cycles or after ovarian hyperstimulation for in-vitro fertilization/gamete intra-Fallopian transfer
Levels of reproductive steroids and gonadotrophins were analysed retrospectively during the peri-implantation period following non-conceptional and conceptional natural cycles and in cycles associated with ovarian hyperstirnulation for in-vitro fertilization or gamete intra-Fallopian transfer. In cy...
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Veröffentlicht in: | Human reproduction (Oxford) 1990-05, Vol.5 (4), p.476-480 |
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Sprache: | eng |
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Zusammenfassung: | Levels of reproductive steroids and gonadotrophins were analysed retrospectively during the peri-implantation period following non-conceptional and conceptional natural cycles and in cycles associated with ovarian hyperstirnulation for in-vitro fertilization or gamete intra-Fallopian transfer. In cycles not associated with conception, the luteal phase of hyperstimulated cycles (n = 100) was characterized by higher serum progesterone and oestradiol levels (P < 0.01) and with an earlier decline in steroids than in natural cycles (n = 21). On day 11 (day of oocyte recovery = day 0), the level of progesterone in twin (n = 59) and triplet (n = 13) pregnancies was higher than singleton pregnancies (n = 176) (P < 0.006, P < 0.006 respectively) while those destined to abort (n = 66) had lower progesterone levels (P < 0.01). Ectopic implantation (n = 11) had the lowest progesterone concentrations on day 11 (P < 0.01) and this may imply a delay in corpus luteum rescue or a later implantation time than intrauterine conception. |
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ISSN: | 0268-1161 1460-2350 |
DOI: | 10.1093/oxfordjournals.humrep.a137127 |