Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells
Covalent attachment of ubiquitin to cellular proteins is essential for cell viability and is catalysed by a set of distinct ubiquitin-conjugating enzymes. Individual members of this novel enzyme family mediate strikingly diverse functions, including DNA repair, cell cycle control, selective protein...
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Veröffentlicht in: | Trends in biochemical sciences (Amsterdam. Regular ed.) 1990-05, Vol.15 (5), p.195-198 |
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container_title | Trends in biochemical sciences (Amsterdam. Regular ed.) |
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creator | Jentsch, Stefan Seufert, Wolfgang Sommer, Thomas Reins, Hans-Albert |
description | Covalent attachment of ubiquitin to cellular proteins is essential for cell viability and is catalysed by a set of distinct ubiquitin-conjugating enzymes. Individual members of this novel enzyme family mediate strikingly diverse functions, including DNA repair, cell cycle control, selective protein degradation and essential functions of the stress response. |
doi_str_mv | 10.1016/0968-0004(90)90161-4 |
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subjects | Cells - enzymology Eukaryotic Cells - enzymology Ligases - physiology Ubiquitin-Protein Ligases |
title | Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells |
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