Successful Treatment of Trichosporon beigelii Pneumonia with Itraconazole

Among patients with neoplastic diseases who are undergoing myeloablation, a growing number of uncommon fungal pathogens (including Trichosporon beigelii) have been reported to cause infection. Amphotericin B has limited activity against T. beigelii. On the basis of in vitro studies, some authors have suggested treatment with triazole compounds. We describe a patient with T. beigelii pneumonia whose condition responded to therapy with itraconazole.