Lipid-based blood-pool CT imaging of the liver

We have recently developed an iodinated lipid-based contrast agent capable of residing in the blood pool for extended periods of time relative to conventional water-soluble contrast agents. The purpose of this study was to examine the effects of combining this new blood-pool agent (ITG-PEG) with a h...

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Veröffentlicht in:	Academic radiology 1998-04, Vol.5, p.S16-S19
Hauptverfasser:	Weichert, Jamey P., Lee, Fred T., Longino, Marc A., Chosy, Susan G., Counsell, Raymond E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cholesterol - administration & dosage Cholesterol - pharmacokinetics Contrast Media - administration & dosage Contrast Media - pharmacokinetics Emulsions - administration & dosage Emulsions - pharmacokinetics Female Liver Neoplasms, Experimental - diagnostic imaging Polyethylene Glycols - administration & dosage Polyethylene Glycols - pharmacokinetics Rabbits Rats Rats, Sprague-Dawley Tomography, X-Ray Computed Triglycerides - administration & dosage Triglycerides - pharmacokinetics Triolein - administration & dosage Triolein - pharmacokinetics
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Beschreibung
Zusammenfassung:	We have recently developed an iodinated lipid-based contrast agent capable of residing in the blood pool for extended periods of time relative to conventional water-soluble contrast agents. The purpose of this study was to examine the effects of combining this new blood-pool agent (ITG-PEG) with a hepatocyte-selective agent (ITG-LE, Molecular Biosystems) for accurate CT detection of small (
ISSN:	1076-6332 1878-4046
DOI:	10.1016/S1076-6332(98)80047-0