Bisphosphonates: a potential role in the prevention of osteoporosis in laying hens

Bisphosphonates: a potential role in the prevention of osteoporosis in laying hens

Osteoporosis in layers is associated with the modelling and remodelling of medullary bone. Cancellous bone volume ( CBV) decreases initially during medullary bone modelling and continues to decrease during subsequent remodelling. In an attempt to maintain peak structural bone mass, the bisphosphonat...

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Veröffentlicht in:Research in veterinary science 1998, Vol.64 (1), p.37-40
Hauptverfasser: Wilson, S., Solomon, S.E., Thorp, B.H.
Format: Artikel
Sprache:eng
Schlagworte:
Alendronate - therapeutic use
Animals
Bone and Bones - cytology
Bone and Bones - drug effects
Bone and Bones - pathology
Bone Density - drug effects
Bone Remodeling - drug effects
Bone Remodeling - physiology
Chickens
Female
Osteoporosis - pathology
Osteoporosis - prevention & control
Osteoporosis - veterinary
Oviposition
Poultry Diseases
Space life sciences
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Zusammenfassung:Osteoporosis in layers is associated with the modelling and remodelling of medullary bone. Cancellous bone volume ( CBV) decreases initially during medullary bone modelling and continues to decrease during subsequent remodelling. In an attempt to maintain peak structural bone mass, the bisphosphonate, alendronate, was administered to pullets before medullary bone modelling. At point of lay CBV was significantly greater (P
ISSN:0034-5288
1532-2661
DOI:10.1016/S0034-5288(98)90112-6