Ribozymes as Therapeutic Agents: Are We Getting Closer?
An editorial addresses a study by Yamazaki et al in which they extend the utility of ribozymes for target validation in human cancer. A hammerhead ribozyme targeting an aberrantly spliced epidermal growth factor receptor transcript is capable of cleaving its target in vitro.
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Veröffentlicht in: | JNCI : Journal of the National Cancer Institute 1998-04, Vol.90 (8), p.558-559 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | An editorial addresses a study by Yamazaki et al in which they extend the utility of ribozymes for target validation in human cancer. A hammerhead ribozyme targeting an aberrantly spliced epidermal growth factor receptor transcript is capable of cleaving its target in vitro. |
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ISSN: | 0027-8874 1460-2105 |
DOI: | 10.1093/jnci/90.8.558 |