Inhibition of rate of tumour growth in rodent species by inoculation of herpesviruses and encephalomyocarditis virus

Inoculation of herpesviruses and encephalomyocarditis virus into subcutaneous tumours in hamsters and mice reduced the rate of tumour growth compared to untreated tumours or secondary tumours which had arisen following surgical excision of the primary tumour; in addition, survival times were increas...

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Veröffentlicht in:Journal of medical virology 1990-03, Vol.30 (3), p.211-215
Hauptverfasser: Cowan, M., Davies, J., Brookes, K., Billstrom, M., McLeish, P., Buchan, A., Skinner, G. R. B.
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Sprache:eng
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Zusammenfassung:Inoculation of herpesviruses and encephalomyocarditis virus into subcutaneous tumours in hamsters and mice reduced the rate of tumour growth compared to untreated tumours or secondary tumours which had arisen following surgical excision of the primary tumour; in addition, survival times were increased in animals whose tumours were inoculated with virus. It is suggested that the role of virus in the modification of tumour growth merits further exploration.
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.1890300313