Merkel Cell Carcinoma: Report of Three Cases

Three cases of Merkel cell carcinoma are reported: Case 1 on the upper eyelid with regional lymph node metastasis, Case 2 with spontaneous regression after repeated biopsies, and Case 3 presumably developing on the lesion of pre‐existing Bowen's disease. In Case 2, the biopsy specimen was chara...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of dermatology 1998-01, Vol.25 (1), p.45-50
Hauptverfasser:	Okamoto, Osamu, Yoshiyama, Masako, Takayasu, Susumu, Yokoyama, Shigeo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Apoptosis Biopsy Bowen's disease Bowen's Disease - pathology Bowen's Disease - surgery Carcinoma, Merkel Cell - pathology Carcinoma, Merkel Cell - radiotherapy Carcinoma, Merkel Cell - secondary Carcinoma, Merkel Cell - surgery Cell Nucleus - ultrastructure Cheek - pathology Cytoplasmic Granules - ultrastructure Eyelid Neoplasms - pathology Eyelid Neoplasms - radiotherapy Eyelid Neoplasms - surgery Facial Neoplasms - pathology Facial Neoplasms - radiotherapy Facial Neoplasms - surgery Follow-Up Studies Humans injury Lymphatic Metastasis Lymphocytes - pathology Male Merkel cell carcinoma Microscopy, Electron Neoplasm Regression, Spontaneous Neoplasms, Multiple Primary - pathology Phosphopyruvate Hydratase - analysis Remission Induction Skin Neoplasms - pathology Skin Neoplasms - surgery spontaneous regression
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Three cases of Merkel cell carcinoma are reported: Case 1 on the upper eyelid with regional lymph node metastasis, Case 2 with spontaneous regression after repeated biopsies, and Case 3 presumably developing on the lesion of pre‐existing Bowen's disease. In Case 2, the biopsy specimen was characterized by numerous apoptotic cells in the periphery of the tumor nests surrounded by lymphocytic infiltration. In Case 3, the tumor developed after injury to the pre‐existing lesion of Bowen's disease.
ISSN:	0385-2407 1346-8138
DOI:	10.1111/j.1346-8138.1998.tb02345.x