Stimulus-secretion coupling in vascular endothelial cells

In this review, we concentrate on the regulation rather than the biochemical mechanisms of secretion. Our limited discussion cannot take into account the extensive and important functional diversity of endothelium through the vascular tree. The selection of agents for more detailed description is li...

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Veröffentlicht in:	Annual review of physiology 1990-01, Vol.52 (1), p.661-674
Hauptverfasser:	NEWBY, A. C, HENDERSON, A. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biomechanical Phenomena Blood vessels and receptors Calcium - metabolism Cytosol - metabolism Diglycerides - metabolism Endothelium, Vascular - cytology Endothelium, Vascular - secretion Fundamental and applied biological sciences. Psychology Growth Substances - secretion Ion Channels - metabolism Nitric Oxide - metabolism Phosphatidylinositols - metabolism Plasminogen Activators - secretion Prostaglandins - metabolism reviews Second Messenger Systems vascular system Vertebrates: cardiovascular system von Willebrand Factor - secretion
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Beschreibung
Zusammenfassung:	In this review, we concentrate on the regulation rather than the biochemical mechanisms of secretion. Our limited discussion cannot take into account the extensive and important functional diversity of endothelium through the vascular tree. The selection of agents for more detailed description is likewise not comprehensive, but is chosen to illustrate principles and experimental approaches.
ISSN:	0066-4278 1545-1585
DOI:	10.1146/annurev.ph.52.030190.003305