Spectral Pathology

We are investigating the use of optical spectroscopy (fluorescence, reflectance, Raman scattering) for detecting precancerous lesions in the mucosal linings of hollow organs. We present a morphological model for extracting quantitative pathological information from fluorescence spectra, using coloni...

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Veröffentlicht in:Annals of the New York Academy of Sciences 1998-02, Vol.838 (1), p.108-115
Hauptverfasser: ZONIOS, GEORGE, COTHREN, ROBERT, CRAWFORD, JAMES M., FITZMAURICE, MARYANN, MANOHARAN, RAMASAMY, VAN DAM, JACQUES, FELD, MICHAEL S.
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container_issue 1
container_start_page 108
container_title Annals of the New York Academy of Sciences
container_volume 838
creator ZONIOS, GEORGE
COTHREN, ROBERT
CRAWFORD, JAMES M.
FITZMAURICE, MARYANN
MANOHARAN, RAMASAMY
VAN DAM, JACQUES
FELD, MICHAEL S.
description We are investigating the use of optical spectroscopy (fluorescence, reflectance, Raman scattering) for detecting precancerous lesions in the mucosal linings of hollow organs. We present a morphological model for extracting quantitative pathological information from fluorescence spectra, using colonic dysplasia as an example. The potential of this technique in providing histological information in real time without the need for tissue removal is discussed.
doi_str_mv 10.1111/j.1749-6632.1998.tb08191.x
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identifier ISSN: 0077-8923
ispartof Annals of the New York Academy of Sciences, 1998-02, Vol.838 (1), p.108-115
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Humans
Intestinal Mucosa - pathology
Precancerous Conditions - pathology
Spectrum Analysis - methods
title Spectral Pathology
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