Spectral Pathology
We are investigating the use of optical spectroscopy (fluorescence, reflectance, Raman scattering) for detecting precancerous lesions in the mucosal linings of hollow organs. We present a morphological model for extracting quantitative pathological information from fluorescence spectra, using coloni...
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Veröffentlicht in: | Annals of the New York Academy of Sciences 1998-02, Vol.838 (1), p.108-115 |
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container_title | Annals of the New York Academy of Sciences |
container_volume | 838 |
creator | ZONIOS, GEORGE COTHREN, ROBERT CRAWFORD, JAMES M. FITZMAURICE, MARYANN MANOHARAN, RAMASAMY VAN DAM, JACQUES FELD, MICHAEL S. |
description | We are investigating the use of optical spectroscopy (fluorescence, reflectance, Raman scattering) for detecting precancerous lesions in the mucosal linings of hollow organs. We present a morphological model for extracting quantitative pathological information from fluorescence spectra, using colonic dysplasia as an example. The potential of this technique in providing histological information in real time without the need for tissue removal is discussed. |
doi_str_mv | 10.1111/j.1749-6632.1998.tb08191.x |
format | Article |
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We present a morphological model for extracting quantitative pathological information from fluorescence spectra, using colonic dysplasia as an example. 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We present a morphological model for extracting quantitative pathological information from fluorescence spectra, using colonic dysplasia as an example. The potential of this technique in providing histological information in real time without the need for tissue removal is discussed.</description><subject>Humans</subject><subject>Intestinal Mucosa - pathology</subject><subject>Precancerous Conditions - pathology</subject><subject>Spectrum Analysis - methods</subject><issn>0077-8923</issn><issn>1749-6632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kL1PwzAQxS0EKqWwsCMhBrYEnx3bMRsqtCBVUImv8WQ7DrSkJMSp1P73JGrUW254793T_Qi5AhpDOzfLGFSiIyk5i0HrNG4sTUFDvDkgw710SIaUKhWlmvFjchLCklJgaaIGZKAFgNJ6SM5fK--a2hSXc9N8l0X5tT0lR7kpgj_r94i8Tx7exo_R7GX6NL6bRY4L1kSOKWkTAAZOgEhFxiWInOeQeetSl1gHSaraOpdLZim1uWLSZcYzCjpjGR-R693dqi7_1j40uFoE54vC_PpyHVBplQhKdWu83RldXYZQ-xyrerEy9RaBYgcEl9h9jd3X2AHBHghu2vBF37K2K5_toz2BVo92-iI0frOXTf2DUnEl8PN5ih_ifsLEfIKK_wNLO2q8</recordid><startdate>19980209</startdate><enddate>19980209</enddate><creator>ZONIOS, GEORGE</creator><creator>COTHREN, ROBERT</creator><creator>CRAWFORD, JAMES M.</creator><creator>FITZMAURICE, MARYANN</creator><creator>MANOHARAN, RAMASAMY</creator><creator>VAN DAM, JACQUES</creator><creator>FELD, MICHAEL S.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19980209</creationdate><title>Spectral Pathology</title><author>ZONIOS, GEORGE ; COTHREN, ROBERT ; CRAWFORD, JAMES M. ; FITZMAURICE, MARYANN ; MANOHARAN, RAMASAMY ; VAN DAM, JACQUES ; FELD, MICHAEL S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c352t-c276b41121c51585d3615f3f1debc8c4bc1487847cf62b00bf726cdae2019d2d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Humans</topic><topic>Intestinal Mucosa - pathology</topic><topic>Precancerous Conditions - pathology</topic><topic>Spectrum Analysis - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ZONIOS, GEORGE</creatorcontrib><creatorcontrib>COTHREN, ROBERT</creatorcontrib><creatorcontrib>CRAWFORD, JAMES M.</creatorcontrib><creatorcontrib>FITZMAURICE, MARYANN</creatorcontrib><creatorcontrib>MANOHARAN, RAMASAMY</creatorcontrib><creatorcontrib>VAN DAM, JACQUES</creatorcontrib><creatorcontrib>FELD, MICHAEL S.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of the New York Academy of Sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ZONIOS, GEORGE</au><au>COTHREN, ROBERT</au><au>CRAWFORD, JAMES M.</au><au>FITZMAURICE, MARYANN</au><au>MANOHARAN, RAMASAMY</au><au>VAN DAM, JACQUES</au><au>FELD, MICHAEL S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Spectral Pathology</atitle><jtitle>Annals of the New York Academy of Sciences</jtitle><addtitle>Ann N Y Acad Sci</addtitle><date>1998-02-09</date><risdate>1998</risdate><volume>838</volume><issue>1</issue><spage>108</spage><epage>115</epage><pages>108-115</pages><issn>0077-8923</issn><eissn>1749-6632</eissn><abstract>We are investigating the use of optical spectroscopy (fluorescence, reflectance, Raman scattering) for detecting precancerous lesions in the mucosal linings of hollow organs. We present a morphological model for extracting quantitative pathological information from fluorescence spectra, using colonic dysplasia as an example. The potential of this technique in providing histological information in real time without the need for tissue removal is discussed.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>9511799</pmid><doi>10.1111/j.1749-6632.1998.tb08191.x</doi><tpages>8</tpages></addata></record> |
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issn | 0077-8923 1749-6632 |
language | eng |
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source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
subjects | Humans Intestinal Mucosa - pathology Precancerous Conditions - pathology Spectrum Analysis - methods |
title | Spectral Pathology |
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