Spectral Pathology

We are investigating the use of optical spectroscopy (fluorescence, reflectance, Raman scattering) for detecting precancerous lesions in the mucosal linings of hollow organs. We present a morphological model for extracting quantitative pathological information from fluorescence spectra, using coloni...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 1998-02, Vol.838 (1), p.108-115
Hauptverfasser:	ZONIOS, GEORGE, COTHREN, ROBERT, CRAWFORD, JAMES M., FITZMAURICE, MARYANN, MANOHARAN, RAMASAMY, VAN DAM, JACQUES, FELD, MICHAEL S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Intestinal Mucosa - pathology Precancerous Conditions - pathology Spectrum Analysis - methods
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	We are investigating the use of optical spectroscopy (fluorescence, reflectance, Raman scattering) for detecting precancerous lesions in the mucosal linings of hollow organs. We present a morphological model for extracting quantitative pathological information from fluorescence spectra, using colonic dysplasia as an example. The potential of this technique in providing histological information in real time without the need for tissue removal is discussed.
ISSN:	0077-8923 1749-6632
DOI:	10.1111/j.1749-6632.1998.tb08191.x