Sera from MS patients and normal controls opsonize myelin

Fc receptor-dependent myelin phagocytosis has been proposed as a mechanism of demyelination in multiple sclerosis (MS). The object of this study was to determine whether MS patients' sera are more opsonic for myelin than normal controls' sera. Opsonization was tested by culturing thioglyco...

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Veröffentlicht in:	Neuroscience letters 1990-02, Vol.109 (3), p.353-356
Hauptverfasser:	Goldenberg, Perry Z., Troiano, Ray A., Kwon, Eunice E., Prineas, John W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological Factors - immunology Cattle Female Humans In Vitro Techniques Macrophage Activation Medical sciences Mice Mice, Inbred DBA Multiple sclerosis Multiple Sclerosis - immunology Multiple Sclerosis - physiopathology Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Myelin Myelin Sheath - immunology Neurology Opsonin Opsonin Proteins Phagocytosis
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