Genetic manipulation of antibiotic-producing Streptomyces

The genetic manipulation of Streptomyces species has been facilitated by the development of versatile cloning vectors, robust gene transfer systems and transposable elements. These molecular genetic tools have been used to construct antibiotic-producing strains with improved properties and recombina...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Trends in microbiology (Regular ed.) 1998-02, Vol.6 (2), p.76-83
1. Verfasser:	Baltz, R H
Format:	Artikel
Sprache:	eng
Schlagworte:	Anthelmintics - metabolism Anti-Bacterial Agents - biosynthesis Antibiotics, Antineoplastic - biosynthesis Gene Transfer Techniques Genetic Engineering - methods Genetic Vectors Glycopeptides Macrolides Streptomyces - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The genetic manipulation of Streptomyces species has been facilitated by the development of versatile cloning vectors, robust gene transfer systems and transposable elements. These molecular genetic tools have been used to construct antibiotic-producing strains with improved properties and recombinants for the production of hybrid glycopeptide and macrolide antibiotics, novel anthelminthic agents and novel cytotoxic anthracyclines.
ISSN:	0966-842X
DOI:	10.1016/s0966-842x(97)01161-x