Antimalarial Xanthones from Garcinia cowa

Antimalarial Xanthones from Garcinia cowa

Abstract Five xanthones from the bark of GARCINIA COWA, namely 7-O-methylgarcinone E (1), cowanin (2), cowanol (3), cowaxanthone (4), and β-mangostin (5), were found to possess IN VITRO antimalarial activity against PLASMODIUM FALCIPARUM with IC 50 values ranging from 1.50 to 3.00 µg/ml. Complete 1...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Planta medica 1998-02, Vol.64 (1), p.70-72
Hauptverfasser: Likhitwitayawuid, Kittisak, Phadungcharoen, Thatree, Krungkrai, Jerapan
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antimalarials - chemistry
Antimalarials - pharmacology
Biological and medical sciences
General pharmacology
Letters
Magnetic Resonance Spectroscopy
Medical sciences
Molecular Structure
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plants, Medicinal - chemistry
Plasmodium falciparum - drug effects
Xanthenes - chemistry
Xanthenes - pharmacology
Xanthones
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Abstract Five xanthones from the bark of GARCINIA COWA, namely 7-O-methylgarcinone E (1), cowanin (2), cowanol (3), cowaxanthone (4), and β-mangostin (5), were found to possess IN VITRO antimalarial activity against PLASMODIUM FALCIPARUM with IC 50 values ranging from 1.50 to 3.00 µg/ml. Complete 1 H- and 13 C-NMR assignments of these compounds are also reported.
ISSN:0032-0943
1439-0221
DOI:10.1055/s-2006-957370